Mycobacterium bovis antibiotic susceptibility test: a “new” liquid method

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INTRODUCTION Proportion method is the most widely used susceptibility test and is considered the reference method for M.tuberculosis (2). When adopted to slow growing strains, such as M. bovis, it couldn’t produce results on time. In addition, this method cannot be applied to pyrazinamidase activity test (PZAase test), which is used to differentiate between M. bovis and M. bovis subsp. caprae (1). The aim of this study was to evaluate the liquid VersaTREK (VT) pyrazinamide (PZA) susceptibility test as an alternative method able to rule out the major errors reported with others broth-based systems (3) and to check if the results obtained with the VT method support the use of a reduced incubation time (from 35 to 13 days). Mycobacterium bovis antibiotic susceptibility test: a “new” liquid method

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تاریخ انتشار 2014